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See Your HPLC Separation
Before the Injection.

ChromSword Offline uses advanced retention modeling to simulate HPLC separations and explore the effects of gradient, pH, and temperature — often from as few as two experimental runs. Less trial and error. More understanding.

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100% Offline & Secure

35 Years Expertise

Everything you need for
method development

Powerful subscription software designed for analytical chemists who need results fast and secure.

Powerful Modeling

Begin modelling your HPLC conditions from just two experimental runs. Evaluate model-based separation conditions before committing to additional lab work.

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User-Friendly

Intuitive, step-based wizard interface designed specifically for analysts. Follow a clear sequence from data input to modelling and export.

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Secure & Offline

All data processed locally—no cloud connection required, no data sharing. Your proprietary methods and formulations remain completely secure.

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Simple Process

Computer-assisted method development

ChromSword Offline uses experimental input from just two chromatographic runs to simulate and predict the best conditions for your sample.

Step 1

Start optimisation with data from just two HPLC runs

Our software accepts data import from the major CDS systems and NetCDF files.

Clear step-based wizard workflow for data input and modelling
Automated and manual modelling options
Easy export of modelled conditions

pH

pH Influence

°C

Temperature

Conc.

Concentration

Step 2

Simulate critical parameters

Use dedicated models to evaluate solvent concentration, pH, and temperature effects and identify promising separation conditions before another experiment.

Isocratic & Gradient

Data input for both elution methods is supported

pH Optimization

Model pH influence on selectivity

Temperature

Column temperature effects

Solvent Strength

Mobile phase optimization

Video walkthroughs

See ChromSword Offline in action

Watch practical demonstrations from the ChromSword YouTube channel to see how retention modeling, simulation, and optimization work inside the software.

Workflow with ChromSword Offline

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Modelling of Solvent Concentration

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Modelling of pH and Temperature

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Backed by 35 years of expertise in liquid chromatography

ChromSword brings decades of chromatography know-how into a simple, powerful subscription tool. Save valuable lab time and find optimal separation conditions with minimal experimental data.

Suitable for isocratic & gradient

No internet required

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Choose Your Plan

Flexible subscriptions
for every lab

Select the subscription that fits your project timeline. All plans include full software access and updates, with expert support and personalised training available as optional add-ons.

3 Months

€ 999

Perfect for short-term projects

Full software license key
Free video training included
Free updates during subscription

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6 Months

€ 1700

12 Months

€ 2500

Continuous development access

Full software license key
Personal online training (€200 value)
All updates + priority support

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Prices are shown excluding VAT. The applicable VAT is calculated during checkout based on the customer's legal status and country of residence.

Need Extended Support?

+3 Months Support

€150

+6 Months Support

€250

+12 Months Support

€400

Secure Payment Options

CARD

Stripe — Secure Card Payment

BANK

Direct Bank Transfer — Corporate Orders

VAT

Tax Invoice — VAT Calculated at Checkout

License Delivery

Receive your download link and license key within one business day. Includes tax invoice and full legal compliance documentation.

One-Business-Day License Delivery

Why add expert support?

Choose expert support for direct technical and scientific guidance from experienced ChromSword specialists.

Troubleshooting

Direct assistance with unexpected errors and technical issues.

Active Email Support

Guidance for data setup, software functions, and technical questions, with responses within one business day.

Scientific Consultation

Expert guidance on simulation design, experiment planning, and computational screening selection for reliable model inputs.

Training Available

Free prerecorded videos are included, or add a personalised two-hour live session tailored to your workflow for €200.

Ready to accelerate your HPLC method development?

Join 500+ laboratories using ChromSword. Subscribe today and receive your license within one business day.

Response Time

Within 1 Business Day

Use the dedicated demo or quotation request so our team can route your inquiry correctly from the start.

Start Your Subscription

Choose a license online, schedule a software demonstration, or request a tailored quotation.

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Payments are completed through the existing secure checkout flow.

See Your HPLC Separation
Before the Injection.